umbrella trial umbrella trial
A research study that tests and compares two or more study treatments for one disease or condition.
Example of umbrella trial in a sentence
In an umbrella trial, multiple study treatments are compared in a single disease or condition.
More Info
An umbrella trial is a type of randomized controlled trial (RCT). It is also a type of Master Protocol Study.
An umbrella trial uses a Master Protocol to compare different study treatments in the same way, using the same design, in a certain disease or condition.
The difference between a basket and an umbrella trial is that a basket trial uses one drug to test against multiple diseases while an umbrella trial studies different drugs in a single disease.
Other info to think about when joining a study
You may hear about umbrella trials when you are learning about different types of study designs.
If you are unsure about what it means for a research study to be an umbrella trial, you should ask a member of the study team to clarify any of your questions.
